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TP53 p.C135fs*35 Reference Standard

CBP10170

產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫(kù)
Introduction 
Format Genomic DNA
Description TP53 C135fs results in a change in the amino acid sequence of the Tp53 protein beginning at aa 135 of 393, likely resulting in premature truncation of the functional protein (UniProt.org). Due to disruption of the DNA-binding domain and loss of the oligomerization domain (UniProt.org), C135fs is predicted to lead to a loss of Tp53 protein function.
   
Technical Data 
DNA Change c.403delT
AA Change p.C135fs*35
Mutation type Deletion - Frameshift
Zygosity Heterozygous
Allelic Frequency 50.00%
Transcript ENST00000269305
Cosmic ID N/A
Chr position(GRCh37) chr17:7578527
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

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