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Package-Ref? Lung Cancer Reference Standard Package

CBP90022

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索取COA

產(chǎn)品描述

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Package-Ref™ Lung Cancer Reference Standard Package
Format	Genomic DNA
Description	包含6管標(biāo)準(zhǔn)品，作為參考品、質(zhì)控品、精密度、檢測限

Panel-Ref® gDNA Cocktail III Reference Standard
Gene	AA Change	CDS Change	Exon	Cosmic ID	Expected AF	Chr position (GRCh37)
EGFR	p.E746_A750delELREA	c.2235_2249del15 GGAATTAAGAGAAGC>-	19	COSM6223	5%	chr7:55242465_55242479
EGFR	p.L858R	c.2573T>G	21	COSM6224	5%	chr7:55259515
EGFR	p.T790M	c.2369C>T	20	COSM6240	5%	chr7:55249071
EGFR	p.G719S	c.2155G>A	18	COSM6252	5%	chr7:55241707
BRAF	p.V600E	c.1799T>A	15	COSM476	內(nèi)源突變	chr7:140453136
KRAS	p.G12D	c.35G>A	2	COSM521	5%	chr12:25398284
KRAS	p.Q61H	c.183A>C	3	COSM554	內(nèi)源突變	chr12:25380275
PIK3CA	p.E545K	c.1633G>A	10	COSM763	5%	chr3:178936091
PIK3CA	p.H1047R	c.3140A>G	20	COSM775	內(nèi)源突變	chr3:178952085
EML4-ALK	E13-A20	DNA Translocation	N/A	COSF408	5%	N/A
CCDC6-RET	E1-E12	DNA Translocation	N/A	COSF1271	5%	N/A
ERBB2	CNV	Amplication	N/A	N/A	CN=6	N/A
MYC	CNV	Amplication	N/A	N/A	CN=10	N/A

Panel-Ref® gDNA Cocktail IV Reference Standard
Gene	AA Change	CDS Change	Exon	Cosmic ID	Expected AF	Chr position (GRCh37)
EGFR	p.G719S	c.2155G>A	18	COSM6252	5%	chr7:55241707
BRAF	p.V600K	c.1798_1799GT>AA	15	COSV56057713	5%	chr7:140453136_140453137
PIK3CA	p.H1047R	c.3140A>G	20	COSM775	5%	chr3:178952085
KRAS	p.G13D	c.38G>A	2	COSM532	5%	chr12:25398281
NRAS	p.G12D	c.182A>G	3	COSM584	5%	chr1:115258747
BRCA2	p.I2675Dfs*6	c.8021dup	18	COSM2071519	5%	chr13:32937360
SLC34A2-ROS1	E4-E32	DNA Translocation	N/A	COSF1197	5%	N/A
EML4-ALK	E6-A20	DNA Translocation	N/A	COSF408	5%	N/A
CCDC6-RET	E1-E12	DNA Translocation	N/A	COSF1271	5%	N/A
MET	Exon 14 Skippig	c.3082+1G>T	N/A	COSM6108462	5%	chr7:116412044
ERBB2	CNV	Amplication	N/A	N/A	CN=6	N/A
MYC	CNV	Amplication	N/A	N/A	CN=7	N/A

Panel-Ref® gDNA Cocktail V Reference Standard
Gene	AA Change	CDS Change	Exon	Cosmic ID	Expected AF	Chr position (GRCh37)
EGFR	p.E746_A750delELREA	c.2235_2249del15 GGAATTAAGAGAAGC>-	19	COSM6223	3%	chr7:55242465_55242479
EGFR	p.L858R	c.2573T>G	21	COSM6224	3%	chr7:55259515
EGFR	p.T790M	c.2369C>T	20	COSM6240	3%	chr7:55249071
EGFR	p.G719S	c.2155G>A	18	COSM6252	3%	chr7:55241707
BRAF	p.V600E	c.1799T>A	15	COSM476	內(nèi)源突變	chr7:140453136
KRAS	p.G12D	c.35G>A	2	COSM521	3%	chr12:25398284
KRAS	p.Q61H	c.183A>C	3	COSM554	內(nèi)源突變	chr12:25380275
PIK3CA	p.E545K	c.1633G>A	10	COSM763	3%	chr3:178936091
PIK3CA	p.H1047R	c.3140A>G	20	COSM775	內(nèi)源突變	chr3:178952085
EML4-ALK	E13-A20	DNA Translocation	N/A	COSF408	3%	N/A
CCDC6-RET	E1-E12	DNA Translocation	N/A	COSF1271	3%	N/A
ERBB2	CNV	Amplication	N/A	N/A	CN=4	N/A

Panel-Ref® gDNA Cocktail VI Reference Standard
Gene	AA Change	CDS Change	Exon	Cosmic ID	Expected AF	Chr position (GRCh37)
BRAF	p.V600E	c.1799T>A	15	COSM476	5%	chr7:140453136
PIK3CA	p.H1047R	c.3140A>G	20	COSM775	5%	chr3:178952085
KRAS	p.G13D	c.38G>A	2	COSM532	5%	chr12:25398281
BRCA2	p.I2675Dfs*6	c.8021dup	18	COSM2071519	5%	chr13:32937360

Panel-Ref® gDNA Cocktail Ⅶ Reference Standard
Gene	AA Change	CDS Change	Exon	Cosmic ID	Expected AF	Chr position (GRCh37)
EGFR	p.E746_A750del	c.2236_2250del15	19	COSM6225	5%	chr7:55242466_55242480
EGFR	p.S768I	c.2303G>T	20	COSM6241	5%	chr7:55249005
EGFR	p.L861Q	c.2582T>A	21	COSM6213	5%	chr7:55259524
MET	CNV	Amplification	N/A	N/A	CN=6	N/A
ERBB2	p.A775_G776insYVMA	c.2324_2325ins12	20	COSM12558	5%	chr17:37880996_37880997
KRAS	p.G12V	c.35G>T	2	COSM520	5%	chr12:25398284
PIK3CA	p.E542K	c.1624G>A	10	COSM760	5%	chr3:178936082
KRAS	p.Q61H	c.183A>C	3	COSM554	5%	chr12:25380275
BRAF	p.V600E	c.1799T>A	15	COSM476	內(nèi)源突變	chr7:140453136
PIK3CA	p.H1047R	c.3140A>G	20	COSM775	內(nèi)源突變	chr3:178952085
EGFR	p.G719C	c.2155G>T	18	COSM6253	5%	chr7:55241707
CD74-ROS1	E6-E34	DNA Translocation	N/A	COSF1200	5%	N/A
NRAS	p.Q61K	c.181C>A	3	COSM580	5%	chr1:115256530
IDH1	p.R132C	c.394C>T	4	COSM28747	5%	chr2:209113113

陰性對照
Mutation	0%
Fusion	0%
Expected %AF	CN=2

Product Information
Intended Use	Research Use Only
Unit Size	1ug/vial * 6 vial
Concentration	Download for COA
Purity	Download for COA
DNA electrophoresis	Download for COA
Storage	2-8°C
Expiry	36 months from the date of manufacture

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上一篇：Panel-Ref? gDNA Cocktail Ⅷ Reference Standard

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