hIL18 Effector Reporter Cell
CBP74173
詢 價(jià)
索取Protocol
產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫(kù)
I. Background | |
Interleukin-18 (IL18, also known as interferon-gamma inducing factor or IGIF) is a cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. Its biological activity is pleiotropic and it has been shown to induce interferon-gamma production in KG-1 cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production in B cells. | |
II.Introduction | |
Expressed gene: | hIL18 |
Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Synonym(s): | IL18; IGIF; IL-18; IL-1g; IL1F4; interleukin 18 |
Freeze Medium: | 90% FBS+10%DMSO |
Culture Medium: | RPMI-1640+10%FBS+1ug/ml puromycin+800ug/ml hygromycin+10ug/ml blasticidin |
Mycoplasma Testing: | Negative |
Storage: | Liquid nitrogen |
Application(s): | Functional(Report Gene) Assay |
III. Representative Data | |
Figure 1.Dose Response of Recombinant IL-18 in IL-18 Effector Reporter Cells(C12). |
|
Figure 2.Inhibition of hIL18-Induced Reporter Activity By Recombinant Human IL18 BP Protein in hIL18 Effector Reporter Cells(C12). |
|