hCLDN6(Claudin6)/CT26
CBPG0053
詢 價
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產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫
I. Background | |
CLDNs 是上皮細(xì)胞緊密連接的主要成分。CLDN6 是緊密連接家族(CLDNs)的一員,是一個四次跨膜蛋白,具有較短的胞質(zhì) N 端和 C 端胞質(zhì)結(jié)構(gòu)域、兩個胞外結(jié)構(gòu)域(較大的 ECL1 和較小的 ECL2)和一個短的胞內(nèi)環(huán)。CLDN6 可參與乳腺癌、胃癌、肝細(xì)胞癌等多種惡性腫瘤的發(fā)生發(fā)展。CLDN6 具有重要的生物學(xué)功能,其異常表達(dá)與丙型肝炎感染有關(guān)。 | |
II. Introduction | |
Host Cell: | CT26 |
Expressed gene: | hCLDN6 |
Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | RPMI-1640+10%FBS+5ug/ml puromycin |
Mycoplasma Testing: | Negative |
Storage: | Liquid nitrogen |
III. Description of Host Cell Line | |
Organism: | Mouse |
Tissue: | colon, metastatic |
Morphology: | N/A |
Growth Properties: | monolayer |
IV. Representative Data | |
Figure 1. Recombinant hCLDN6(Claudin6)/CT26 stably expressing CLDN6. |
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