TSHR CHO
CBP71474
詢 價
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產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫
| I. Background | |
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TSHR (Thyroid Stimulating Hormone Receptor) is a Protein Coding gene. Diseases associated with TSHR include Hypothyroidism, Congenital, Nongoitrous, 1 and Hyperthyroidism, Familial Gestational. Among its related pathways are Class A/1 (Rhodopsin-like receptors) and GPCR downstream signalling. |
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| II. Description | |
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TSHR CHO 報告基因藥靶模型很好的模擬了體內 TSHR 的信號轉導過程，原理見下圖所示。 |
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| Figure 1. TSHR CHO 細胞模型原理圖
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| III. Introduction | |
| Expressed gene: | TSHR |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | F12K+10%FBS+5μg/ml Puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Functional assay for TSHR receptor |
| Transducer: | Gs |
IV. Representative Data Figure 2. Recombinant TSHR CHO stably expressing TSHR.  |
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Figure 3. HTRF cAMP Assay with TSHR CHO(C11). Figure 4. HTRF cAMP Assay with TSHR CHO(C11). |
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