hCLEC12A/C1498
CBPG0134
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I. Background | |
CLEC12A 屬于 C-型凝集素/C-型凝集素樣結(jié)構(gòu)域(CTL/CTLD)超家族的一員。這個(gè) 家族的成員共享一個(gè)共同的蛋白質(zhì)折疊,并具有多種功能,如細(xì)胞粘附、細(xì)胞間信號(hào)傳導(dǎo)、 糖蛋白代謝和參與炎癥和免疫應(yīng)答。CLEC12A 基因編碼的蛋白質(zhì)是粒細(xì)胞和單核細(xì)胞功能 的負(fù)調(diào)控因子,參與免疫系統(tǒng)的平衡調(diào)節(jié)。CLEC12A 在自身免疫性疾病如風(fēng)濕性關(guān)節(jié)炎和 多發(fā)性硬化癥的發(fā)展中發(fā)揮著重要作用。 | |
II. Introduction | |
Host Cell: | C1498 |
Expressed gene: | hCLEC12A |
Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | DMEM+10%FBS+2μg/ml puromycin |
Mycoplasma Testing: | Negative |
Storage: | Liquid nitrogen |
III. Description of Host Cell Line | |
Organism: | Mus musculus, mouse |
Tissue: | N/A |
Morphology: | lymphoblast |
Growth Properties: | Suspension |
IV. Representative Data Figure 1. Recombinant hCLEC12A/C1498 stably expressing hCLEC12A. |