hFXR Reporter Cell
CBPM0006
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| I. Background | |
| The farnesoid X receptor (FXR, NR1H4)2 is a member of the nuclear receptor (NR) superfamily that plays a key role in the regulation of bile acids, lipid, and glucose metabolisms, as well as anti-inflammatory response and hepatocarcinogenesis inhibition . FXR, which is abundantly expressed in liver, kidney, and intestine, has been identified as the main bile acid sensor . | |
| II. Introduction | |
| Expressed gene: | hFXR |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM+10%FBS+2ug/ml puromycin+200ug/ml hygromycin |
| Storage: | Liquid nitrogen |
| III. Representative Data | |
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Figure 1. Dose Response of CPDs in hFXR Reporter Cells (C1). |
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