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首頁(yè) /藥靶模型 /藥靶細(xì)胞 /GPCR靶點(diǎn) /CXCR5/CHO

CXCR5/CHO

CBP71370

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I. Background
CXCR5 (C-X-C Motif Chemokine Receptor 5) is a Protein Coding gene. Diseases associated with CXCR5 include Intraocular Lymphoma and Lymphoma. Among its related pathways are CCR5 Pathway in Macrophages and Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and C-X-C chemokine receptor activity. 
 
II. Introduction
Host Cell:

CHO

Stability: 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium: 90% FBS+10% DMSO
Culture Medium: F12K+10%FBS+5ug/ml puromycin
Mycoplasma Status: Negative
Storage: Liquid nitrogen immediately upon delivery
Application(s):

Functional assay for CXCR5 receptor

Transducer: Gi
 
Ⅲ. Description of Host Cell Line
Organism: Hamster
Tissue: Ovary
Morphology: Epithelial
Growth Properties: Adherent
 
Ⅳ. Representative Data

Figure 1. Recombinant CXCR5/CHO cell line expressing CXCR5.

Figure 2. RD CXCL13 effect on CHO-CXCR5 clone 5.


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