pc-12（大鼠腎上腺嗜鉻細(xì)胞瘤細(xì)胞）
CBP60430
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| I. General information | |
| Synonyms: | pc-12低分化 |
| Background: | The PC-12 cell line was derived from a transplantable rat pheochromocytoma. |
| Species: | Rattus norvegicus, rat |
| Tissue: | adrenal gland |
| Disease: | pheochromocytoma |
| Gender: | male |
| Morphology: | small irregularly shaped cells |
| Growth Mode: | floating clusters; few scattered lightly attached cells. |
| Doubling Time: | 48 hrs |
| DNA Profile: | Cobioer’s Cell Line Authentication Service |
| Culture Medium: |
RPMI 1640+10% Horse Serum+5%FBS pc-12完全培養(yǎng)基，# CBP60430M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Antigen Expression: | N/A |
| Receptor Expression: | nerve growth factor (NGF), expressed |
| Oncogene: | N/A |
| Genes Expressed: | catecholamines; dopamine; norepinephrine |
| Cellular Products: | catecholamines; dopamine; norepinephrine |
| Tumor Formation: | Yes, in New England Deaconess Hospital strain rats |
| Comments: | The cells respond reversibly to NGF by induction of the neuronal phenotype when plated on Collagen IV coated culture flasks. The cells do not synthesize epinephrine. For more information, please contact Cobioer (4008-750-250). |
