Panc 02.03（人胰腺腺癌細(xì)胞）
CBP60681
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| I. General information | |
| Synonyms: | Panc 02.03 |
| Background: | Panc 02.03 is a pancreatic adenocarcinoma epithelial cell line derived in 1995 from a primary tumor removed from the head-of-the-pancreas of a female with pancreatic adenocarcinoma. |
| Species: | Homo sapiens, human |
| Tissue: | pancreas |
| Disease: | adenocarcinoma |
| Gender: | White, female, 70 years |
| Morphology: | epithelial |
| Growth Mode: | adherent |
| Doubling Time: | 28.2 hrs |
| DNA Profile: | Amelogenin: X CSF1PO: 11,12 D13S317: 12 D16S539: 11 D5S818: 12,13 D7S820: 9,10 THO1: 6 TPOX: 9,12 vWA: 17 Cobioer’s Cell Line Authentication Service |
| Culture Medium: |
RPMI-1640+15%FBS+10ug/ml insulin Panc 02.03完全培養(yǎng)基，# CBP60681M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Antigen Expression: | MHC class I +; MHC class II -,Ref |
| Oncogene: | K-ras + Ref |
| Genes Expressed: | cytokeratins 7 and 18, Ref |
| Cellular Products: | cytokeratins 7 and 18, Ref |
| Tumor Formation: | Yes, forms tumors in nude or SCID mice,Ref |
| Comments: | The cell line exhibits a K-ras oncogene mutation at codon 12 where a GGT --> GAT mutation resulted in substitution of aspartic acid for glycine. The cells have a reported plating efficiency of 100% For more information, please contact Cobioer (4008-750-250). |
