Panc 04.03(人胰腺腺癌細(xì)胞)
CBP60683
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產(chǎn)品描述
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I. General information | |
Synonyms: | Panc 04.03 |
Background: | Panc 04.03 is a pancreatic adenocarcinoma epithelial cell line derived, in 1995, from a primary tumor removed from the head-of-the-pancreas of a male with pancreatic adenocarcinoma. |
Species: | Homo sapiens, human |
Tissue: | pancreas |
Disease: | adenocarcinoma |
Gender: | White, male, 70 years adult |
Morphology: | epithelial |
Growth Mode: | adherent |
Doubling Time: | 20 hrs |
DNA Profile: | Amelogenin: X CSF1PO: 12 D13S317: 11,12 D16S539: 11,12 D5S818: 11 D7S820: 8,12 THO1: 9.3 TPOX: 10,11 vWA: 14,16 Cobioer’s Cell Line Authentication Service |
Culture Medium: |
RPMI-1640+15%FBS+10ug/ml insulin Panc 04.03完全培養(yǎng)基,# CBP60683M |
Cryopreservation medium: | 90%FBS+10%DMSO |
Antigen Expression: | MHC class I +; MHC class II - ,Ref,Blood type O; Rh+ |
Oncogene: | K-ras + Ref |
Genes Expressed: | cytokeratins 7 and 18 Ref |
Cellular Products: | cytokeratins 7 and 18 ref |
Tumor Formation: | Yes, forms tumors in nude or SCID mice |
Comments: | The cell line exhibits a K-ras oncogene mutation at codon 12 where a GGT --> GAT mutation resulted in substitution of aspartic acid for glycine. Ref The cells have a reported plating efficiency of 80%. Ref For more information, please contact Cobioer (4008-750-250). |