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診斷試劑
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Introduction | ||||||
Description | DNA methylation is an epigenetic modification, a form of chemical modification of DNA, which refers to the carbon 5 of cytosine in the genomic CpG dinucleotide under the action of DNA methyltransferase. covalently bonded to a methyl group. It can change genetic expression without changing the DNA sequence. The placenta-specific gene 8 (Plac8) encodes a chromatin-binding protein that was first identified from placenta and that is highly expressed in plasmacytoid dendritic cells.In cancer invasion, possibly through promoting the epithelial-to-mesenchymal transition seen during tumor progression. |
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Technical Data | ||||||
Classification | Cat No. | Name | Unit Size | Methylation level | ||
Chr4:84035895-84035987 (hg19) | ||||||
質(zhì)控品 | 陽性質(zhì)控品 | CBPE0271 | PLAC8 Methylation Positive control | 1ug | 94.20% | |
陰性質(zhì)控品 | CBPE0272 | PLAC8 Methylation Negative control (< Cut off) | 1ug | N/A | ||
參考品 | 強陽性參考品-1 | CBPE0273 | PLAC8 Methylation Reference Standard with > 90% | 1ug | 94.20% | |
強陽性參考品-2 | CBPE0274 | PLAC8 Methylation Reference Standard with 10% | 1ug | N/A | ||
弱陽性參考品 | CBPE0275 | PLAC8 Methylation Reference Standard with 3% | 1ug | N/A | ||
檢測限參考品 | CBPE0276 | PLAC8 Methylation Reference Standard with 1% | 1ug | N/A | ||
陰性參考品 | CBPE0277 | PLAC8 Methylation Negative Reference Standard (< Cut off) | 1ug | 0.00% | ||
精密度參考品 | CBPE0275 | PLAC8 Methylation Reference Standard with 3% | 1ug | N/A | ||
CBPE0277 | PLAC8 Methylation Negative Reference Standard (< Cut off) | 1ug | 0.00% | |||
特異性參考品 | 定制化 | |||||
備注 | 1. 質(zhì)控品也叫準確度標準品,用于定性判斷; 2. 參考品用于定性和定量的判斷,其中強陽、弱陽、檢測限、精密度、特異性的判定需要視具體項目而定,本產(chǎn)品的判定僅為內(nèi)部標準; 3. 質(zhì)控品用于性能評價,出廠檢,試劑盒日常檢測判定,參考品用于性能評價,出廠檢; 4.上述產(chǎn)品只展示了部分結(jié)果,甲基化程度可以定制。 |
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Product Information | ||||||
Intended Use | Research Use Only | |||||
Concentration | Download for COA | |||||
Purity | Download for COA | |||||
DNA electrophoresis | Download for COA | |||||
Storage | 2-8°C | |||||
Expiry | 36 months from the date of manufacture | |||||
Remark | The data in the instruction manual is the data of a single test, and the specific data of each batch is subject to delivery. |