MGMT 甲基化單基因單區(qū)段標(biāo)準(zhǔn)品
CBPE0250-0256
詢 價
索取COA
產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫
| Introduction | ||||||
| Description | DNA methylation is an epigenetic modification, a form of chemical modification of DNA, which refers to the carbon 5 of cytosine in the genomic CpG dinucleotide under the action of DNA methyltransferase. covalently bonded to a methyl group. It can change genetic expression without changing the DNA sequence. MGMT, O-6-methylguanine-DNA methyltransferase, is a DNA repair protein that plays a role in removing DNA adducts and regulates cell death. MGMT fusions have been identified in glioma, and MGMT promoter methylation and loss of MGMT expression has been identified in various tumor types, including lymphoma, glioma, colorectal, non-small cell lung, and head and neck carcinoma. |
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| Technical Data | ||||||
| Classification | Cat No. | Name | Unit Size | Methylation level | ||
| Chr10:131265516-131265596(hg19) | ||||||
| 質(zhì)控品 | 陽性質(zhì)控品 | CBPE0250 | MGMT Methylation Positive control | 1ug | 98.30% | |
| 陰性質(zhì)控品 | CBPE0251 | MGMT Methylation Negative control (< Cut off) | 1ug | 0.00% | ||
| 參考品 | 強陽性參考品-1 | CBPE0252 | MGMT Methylation Reference Standard with > 90% | 1ug | 98.30% | |
| 強陽性參考品-2 | CBPE0253 | MGMT Methylation Reference Standard with 10% | 1ug | 10.92% | ||
| 弱陽性參考品 | CBPE0254 | MGMT Methylation Reference Standard with 3% | 1ug | 3.10% | ||
| 檢測限參考品 | CBPE0255 | MGMT Methylation Reference Standard with 1% | 1ug | 1.10% | ||
| 陰性參考品 | CBPE0256 | MGMT Methylation Negative Reference Standard (< Cut off) | 1ug | 0.00% | ||
| 精密度參考品 | CBPE0254 | MGMT Methylation Reference Standard with 3% | 1ug | 3.10% | ||
| CBPE0256 | MGMT Methylation Negative Reference Standard (< Cut off) | 1ug | 0.00% | |||
| 特異性參考品 | 定制化 | |||||
| 備注 | 1. 質(zhì)控品也叫準(zhǔn)確度標(biāo)準(zhǔn)品，用于定性判斷； 2. 參考品用于定性和定量的判斷，其中強陽、弱陽、檢測限、精密度、特異性的判定需要視具體項目而定，本產(chǎn)品的判定僅為內(nèi)部標(biāo)準(zhǔn)； 3. 質(zhì)控品用于性能評價，出廠檢，試劑盒日常檢測判定，參考品用于性能評價，出廠檢； 4.上述產(chǎn)品只展示了部分結(jié)果，甲基化程度可以定制。 |
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| Product Information | ||||||
| Intended Use | Research Use Only | |||||
| Concentration | Download for COA | |||||
| Purity | Download for COA | |||||
| DNA electrophoresis | Download for COA | |||||
| Storage | 4°C | |||||
| Expiry | 36 months from the date of manufacture | |||||
| Remark | The data in the instruction manual is the data of a single test, and the specific data of each batch is subject to delivery. | |||||
