hCDH6/ID8
CBPG0097
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產品描述
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I. Background | |
CDH6(Cadherin 6,鈣粘蛋白 6) 是一種 II 型鈣粘附素,是鈣粘附素家族的成員之一。 CDH6 對于細胞黏附、胚胎發(fā)育的細胞識別、遷移和組織分化、構成成體器官都有重要作 用。在胚胎發(fā)育過程中,參與胚胎腎形態(tài)形成和發(fā)育,驅動腎形態(tài)發(fā)生所需的間充質-上皮 分化。CDH6 在甲狀腺腫瘤、膽管癌、骨肉瘤、口腔鱗狀細胞癌、黑色素瘤、甲狀腺乳頭 狀癌、鼻咽癌、膠質瘤、胃癌等腫瘤中起到重要作用。CDH6 還可以作為甘氨酰-tRNA 合 成酶(GRS)的功能性受體在人體內部起到抗腫瘤作用。 | |
II. Introduction | |
Host Cell: | ID8 |
Expressed gene: | hCDH6/ID8 |
Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | DMEM+10%FBS+2μg/ml puromycin |
Mycoplasma Testing: | Negative |
Storage: | Liquid nitrogen |
III. Description of Host Cell Line | |
Organism: | Mouse |
Tissue: | Ovarian |
Morphology: | Epithelial |
Growth Properties: | Adherent |
IV. Representative Data | |
Figure 1. Recombinant hCDH6/ID8 stably expressing hCDH6. |
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