c-Kit K642E/BaF3
CBP73332
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產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫(kù)
| I. Introduction | |
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Cell Line Name： |
c-Kit K642E/BaF3 |
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Host Cell: |
Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
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Freeze Medium: |
90% FBS+10% DMSO |
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Complete Culture Medium: |
RPMI-1640+10%FBS |
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Mycoplasma Status: |
Negative |
| II. Background | |
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KIT K642E lies within the tyrosine kinase domain 1 (exon 13) of the Kit protein (PMID: 15990278). K642E results in constitutive phosphorylation of Kit and activation of downstream signaling (PMID: 15990278, PMID: 19802003), as well as transformation of cultured cells (PMID: 11073817). |
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| III. Representative Data | |
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2.Sanger of c-Kit K642E/BaF3
Figure 1. c-Kit K642E/BaF3 K642E |
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3. Anti-proliferation assay |
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