c-Kit Y823D/BaF3
CBP73208
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產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫
I. Introduction | |
Cell Line Name: |
c-Kit Y823D/BaF3 |
Gene Synonyms: |
c--Kit |
Host Cell: |
Ba/F3 |
Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: |
90% FBS+10% DMSO
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Complete Culture Medium: |
RPMI-1640+10%FBS |
Mycoplasma Status: |
Negative |
II. Background |
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KIT Y823D lies within the protein kinase domain of the Kit protein (UniProt.org). Y823D confers a gain of function on Kit, as indicated by constitutive phosphorylation of Kit in cultured cells (PMID: 14695343, PMID: 20633291). |
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III. Representative Data | |
1.WB of c-Kit Y823D/BaF3 |
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2.Sanger of c-Kit Y823D/BaF3 |
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3. Anti-proliferation assay Figure 3. CTG Proliferation Assay of BaF3 c-KIT Y823D (C1). |
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