HCC1395（人乳腺癌細(xì)胞）
CBP60370
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產(chǎn)品描述
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| I. General information | |
| Synonyms: | HCC1395 |
| Background: | This cell line was initiated on 12/14/94 from a patient with a family history of cancer (patient's mother had breast cancer). The cell line took 14 months to establish. |
| Species: | Homo sapiens, human |
| Tissue: | mammary gland; breast/duct |
| Disease: | TNM stage I, grade 3, primary ductal carcinoma |
| Gender: | female, 43 years adult, Caucasian, White |
| Morphology: | epithelial |
| Growth Mode: | adherent |
| DNA Profile: | Amelogenin: X CSF1PO: 11 D13S317: 9 D16S539: 11 D5S818: 11 D7S820: 10,12 THO1: 9.3 TPOX: 11 vWA: 15 Cobioer’s Cell Line Authentication Service |
| Culture Medium: |
RPMI-1640+20%FBS HCC1395完全培養(yǎng)基，# CBP60370M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Receptor Expression: | estrogen receptor, negative according to depositor progesterone receptor, negative |
| Oncogene: | her2/neu -, p53 + |
| Genes Expressed: | Epithelial glycoprotein 2 (EGP2),cytokeratin 19 |
| Cellular Products: | Epithelial glycoprotein 2 (EGP2) cytokeratin 19 |
| Comments: | The tumor was classified as TNM stage I, grade 3, invasive ductal carcinoma with 0 out of 34 lymph node metastasis. The cells are poorly differentiated and vacuolated. The cells are negative for expression of Her2-neu but positive for expression of p53. HCC1395 is positive for the epithelial cell specific marker Epithelial Glycoprotein 2 (EGP2) and for cytokeratin 19. The cells are negative for expression of estrogen receptors (ER -) according to depositor and negative for expression of progesterone receptors (PR -). An EBV transformed lymphoblastoid cell line (HCC1395BL) from the same patient is available as ATCC CRL-2325. For more information, please contact Cobioer (4008-750-250). |
