Her2 WT/BaF3
CBP73110
詢 價
留 言
產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫
| I. Introduction | |
|
Cell Line Name： |
Her2 WT/BaF3 |
|
Host Cell: |
Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
|
Application: |
Anti-proliferation assay and PD assay |
|
Freeze Medium: |
90% FBS+10% DMSO |
|
Complete Culture Medium: |
RPMI-1640+10% FBS |
|
Mycoplasma Status: |
Negative |
| II. Background | |
|
ERBB2 (HER2), erb-b2 receptor tyrosine kinase 2, is an EGFR receptor tyrosine kinase that activates PI3K-AKT-mTOR and RAS-RAF-MEK-ERK pathways, therefore regulating growth and transformation (PMID: 17471238). ERBB2 (HER2) amplification, overexpression, and activation has been implicated in several tumor types (PMID: 17471238). |
|
| III. Representative Data | |
|
1. WB of Her2 WT/BaF3
|
|
|
2. Anti-proliferation assay |
|
|
Figure 2. Anti-proliferation assay of two reference compounds on the Ba/F3_HER2 WT Stable Cell line. |
|
