KRAS G12C/BaF3
CBP73227
詢 價
留 言
產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫
| I. Introduction | |
|
Cell Line Name： |
KRAS G12C/BaF3 |
|
Host Cell: |
Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
|
Application: |
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
| Freeze Medium: | 90% FBS+10% DMSO |
|
Complete Culture Medium: |
RPMI-1640+10%FBS+1ug/ml puromycin |
|
Mycoplasma Status: |
Negative |
| II. Background | |
|
KRAS, KRAS proto-oncogene, GTPase, is a member of the small GTPase superfamily and a key regulator of the MAPK, PI3K/AKT/mTOR pathways (PMID: 23622131). KRAS mutations are identified in a wide range of cancers (PMID: 28666118). |
|
| III. Representative Data | |
|
1.WB of KRAS G12C/BaF3
|
|
|
2.Sanger of KRAS G12C/BaF3
|
|
|
3. Anti-proliferation assay
Figure 3. CTG Proliferation Assay of BaF3 KRAS G12C Cells (C3). |
|
