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首頁 /藥靶模型 /激酶靶點 /AXL /AXL-MBIP/BaF3

AXL-MBIP/BaF3

CBP73274

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I. Introduction

Cell Line Name:

AXL-MBIP/BaF3

Host Cell:

Ba/F3

Stability: 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

RPMI-1640+10%FBS

Mycoplasma Status:

Negative

 
II. Background

AXL, AXL receptor tyrosine kinase, is a receptor tyrosine kinase, which promotes growth, migration, and survival of tumor cells through activation of Mapk signaling (PMID: 28072762). Activation and overexpression of AXL has been associated with resistance to chemotherapeutic agents and targeted therapies (PMID: 28251492), in both solid and hematological tumors (PMID: 32148495).

 
III. Representative Data

1. WB of  AXL-MBIP/BaF3

 

2. Anti-proliferation assay

Figure 2. CTG Proliferation Assay of BaF3 AXL MBIP (C2).

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